nanoFRET projects
He who has a “why” to live for can bear with almost any “how”.
(Friedrich Nietzsche)
Our current and former research projects.
- Breaking the Limits of Sugar Sensing in Plants Using Photon Avalanche FRET (HFSP Research Grant in collaboration with Wolf Frommer from Heinrich Heine University Düsseldorf and Artur Bednarkiewicz from Institute of Low Temperature and Structure Research Wrocław: 2026 – 2029)
- eSENSORs: Training Future Leaders in Next-Generation Environmental Sensors for Real-Time Water Monitoring and Control (CREATE Grant coordinated by David McCarthy from University of Guelph and in collaboration with Université Laval: 2026 – 2032)
- Laboratory for Advanced Nano-Optical Biosensing (John R. Evans Leaders Funds: 2024 – 2027)
- Upconversion materials for energy transfer based biosensing and bioimaging (Discovery Grant: 2024 – 2029)
- Canada Excellence Research Chair (CERC) in Nano-Optical Biosensing and Molecular Diagnostics (2023 – 2031)
- multiTG-miRNAs (2023 – 2025): Early cancer diagnosis by multiple time-resolved detection of miRNAs (WINNINGNormandy Fellowship)
- THERnanoSTICS (2022 – 2024): Development of Theranostic Nanomaterials for Optical Imaging in the NIR-II Window and Photoactivated Chemotherapy (WINNINGNormandy Fellowship)
- FRETiculous (2021 – 2024): Lanthanide-to-quantum dot energy transfer for advanced biosensing and live-cell imaging
- FRET-up (2020 – 2023): Nanoparticules de conversion ascendante pour la biodétection et l’imagerie de fluorescence / Nanoparticelle in grado di dare upconversion per biosensing e imaging basato su fluorescenza (Collaboration with the University of Padova)
- Nanosuspect (2020 – 2023): Nanoparticle-surface-spectroscopy – Probing nanosurface-environment interactions by Förster Resonance Energy Transfer (FRET) from lanthanide complexes to quantum dots (Collaboration with the University of Copenhagen)
- COBRA-FRET (2019 – 2022): Détection et imagerie de fluorescence ultrasensible et multiplexé pour l’analyse des acides nucléiques (Chaire d’Excellence – Réseaux d’Intérêts Normands)
- PLASMOFRET (2021 – 2023): Plasmon-Enhanced FRET for Ultrasensitive Multiplexed Biosensing
- MANBAMM (2022 – 2025): Multicomponent Analysis of Nano-Bio-Assemblies using Microfluidic Modulation
- LaPin (2020 – 2024): Lanthanide-Loaded Polymer Nanoparticles for Autofluorescence-Free In Vitro and In Vivo Biosensing and Imaging
- neutrinos (2016 – 2020): Nanoparticle-Enhanced Ultrasensitive Tracking of Biological Interactions by Optical Sensing
- PhenX (2016 – 2020): Molecular mechanism of Phage-encoded activation of Xer recombination
- amplify (2017 – 2018): Multiplexed diagnostics of microRNA using ultra-sensitive homogeneous FRET detection
- NanoFRET (2012 – 2016): Quantum Dot-based Highly Sensitive Multiplexed FluoroImmunoAssays
- NanoCTC (2011 – 2014): Phenotypic and molecular characterization of circulating tumoral cells relying on the use of photoluminescent nanoparticles to quantify proteins and nucleic acids of interest.
- MULTIPLEX (2021 – 2023): Multiplexed Fluorescence Biosensing with Semiconductor and Polymer Nanoparticles
- ACTION (2021 – 2023): Advanced Diagnostic of Colorectal Cancer: Liquid Biopsy Screening Using Time-Gated FRET
- Upbiosens (2019 – 2021): Near-infrared nucleic acids sensing and imaging using lanthanide-based nanoparticles capped with DNA (Marie Sklodowska-Curie Individual Fellowship of Laura Francés-Soriano)
- GYNO-MIR (2017 – 2020): Place des microARN plasmatiques comme nouveaux biomarqueurs dans les cancers gynécologiques (cancer l’endomètre et de l’ovarie)
- QuantumDope (2016 – 2019): Doped quantum dots for photoluminescence lifetime multiplexing (PhD fellowship of Chi Chen)
- Quanticorps (2016 – 2017): Conjugaison directe entre des boîtes quantiques et des anticorps pour des immunodosages de FRET ultrasensibles
- DARN (2015 – 2016): Détection homogène et multiplexée de microARN
- DNA-FRET (2016 – 2020): DNA Hybridization FRET Assays for Multiplexed Diagnostics (PhD fellowship of Jingyue Xu)
- TR-FRIM (2015 – 2019): Time-resolved multiplexed Förster resonance energy transfers for cell imaging of protein-protein interactions based on Tb complexes and quantum dots (PhD fellowship of Jiajia Guo)
- FRETnostics (2012 – 2016): Development of quantum dot-based time-resolved multiplexed FRET biosensors for in vitro and in vivo diagnostics (PhD fellowship of Xue Qiu)
- UPCON-DNA (2018 – 2019): NIR biosensing using lanthanide-based nanoparticles capped with DNA (Postdoc fellowship of Laura Francés-Soriano)
- PROSEQO (2016 – 2019): Protein Sequencing Using Optical Single Molecule Real-Time Detection
- MultiSens (2015 – 2019): Multiplexed Homogeneous Micro-RNA Sensors and Singlet-Oxygen-Transfer Immunoassays
- nanohype (2015 – 2018): Nanoparticle Hybrid Materials Using Plasmonic-Enhanced Upconversion FRET for Multiplexed Sensing and Optical Barcoding
- AMPLINOSTIC (2016 – 2017): Development of a diagnostic kit for multiplexed detection of micro-RNAs
- NanoTRAM (2015 – 2016): FRET and FLIM nanobiosensors for characterizing nanoparticle-mediated drug delivery and drug efficacy inside the cell
- FRETimage (2014 – 2017): Terbium-to-quantum dot FRET for highly sensitive multiplexed live-cell imaging
- OncoTrack (2011 – 2016): Methods for systematic next generation oncology biomarker development
- NanoSens (2012 – 2015): Systematic Investigations of Semiconductor Nanoparticle Dimensions and Surfaces for FRET-based Biosensing Applications
- NANOGNOSTICS (2009 – 2013): Quantum Dot-Based Highly Sensitive Immunoassays for Multiplexed Diagnostics of Alzheimer’s Disease.