Niko HILDEBRANDT (PhD, Professor)
Canada Excellence Research Chair (CERC) in
Nano-Optical Biosensing and Molecular Diagnostics
McMaster University – Faculty of Engineering
Department of Engineering Physics
Hamilton, ON, L8S 4K1 – CANADA
Contact: nhl@mcmaster.ca
NHL is located on the traditional territories of the Haudenosaunee and Mississauga Nations, and within the lands protected by the Dish With One Spoon wampum agreement.
Multiplexed luminescence biosensing
The Niko Hildebrandt Lab (NHL) is a multidisciplinary team comprised of diverse individuals who are joining their expertises to create and develop novel biosensing technologies and integrate these into real-life bioapplications in cooperation with other academic groups, communities, and industrial partners. Our main focus is the application of Förster Resonance Energy Transfer (FRET) with lanthanide complexes, lanthanide nanoparticles, quantum dot nanocrystals, and organic dyes. Using time-resolved optical spectroscopy and imaging technologies, we fully exploit the unique advantages of these luminescent markers for ultra-sensitive multiplexed detection, e.g., for in vitro diagnostics or live cell investigations.
KEYWORDS: FRET, biosensing, diagnostics, biomarkers, quantum dots, terbium, upconversion, time-resolved, multiplexing, spectroscopy, imaging, DNA, RNA, antibodies